Abbott and Costello
Amy Adams (until the very beginning of The New '10s)
Mark Addy
Jason Alexander
Woody Allen
Steve Allen
Tim Allen
Kirstie Alley
Jennifer Aniston
Aziz Ansari
Noah Antwiler
Christina Applegate
Fatty Arbuckle
Eve Arden
Alan Arkin
Will Arnett
Tom Arnold
David Arquette
Bea Arthur
Jean Arthur
Alexandre Astier
Rowan Atkinson
Dan Aykroyd**
Richard Ayoade
Hank Azaria
Alec Baldwin
Lucille Ball
Elizabeth Banks
Sacha Baron Cohen
Jay Baruchel
Jason Bateman
David Battley, though he mostly did brief supporting roles.
Samantha Bee
Beth Behrs
Kristen Bell
James Belushi**
John Belushi**
H. Jon Benjamin
Michael Bentine
Candice Bergen
Edgar Bergen
Mayim Bialik
Jack Black
Lewis Black
Mel Blanc
Rachel Bloom
Mary Boland
Julie Bowen
Frankie Boyle
Wayne Brady
Zach Braff
Wilfrid Brambell
Russell Brand
Bernard Bresslaw
Alison Brie
Jim Broadbent
Albert Brooks
Mel Brooks
Aidy Bryant**
Carol Burnett
George Burns
Steve Buscemi, though mostly if he's working with Adam Sandler.
Ty Burrell
Peter Butterworth
Rose Byrne
Sid Caesar
Anna Camp
Bruce Campbell
John Candy
Peter Capaldi
Linda Cardellini
Steve Carell
Drew Carey
George Carlin
Jim Carrey
Dana Carvey**
Dan Castellaneta
Tom Cavanagh
John Cena
Michael Cera
Jackie Chan
Dave Chappelle
Charlie Chaplin
Graham Chapman
Dave Chappelle
Chevy Chase**
Cheech and Chong
Kristin Chenoweth
John Cho
Margaret Cho
Louis C.K.
Christian Clavier
Andrew "Dice" Clay
John Cleese
Carol Cleveland
Stephen Colbert
Toni Collette
Olivia Colman
Billy Connolly
Kenneth Connor
Dane Cook
Peter Cook
Steve Coogan
Rob Corddry
Bill Cosby
Miranda Cosgrove
Courteney Cox
Bryan Cranston (rarely since 2008)
Michael Crawford
Terry Crews
Bernard Cribbins
Mackenzie Crook
David Cross
Jon Cryer
Billy Crystal**
Kaley Cuoco
Jane Curtin**
Jim Dale
Rodney Dangerfield
Ted Danson
Larry David
Sammy Davis Jr.
Peter Davison
Shane Dawson
Charlie Day
Felicia Day
Micaela Dee
Eddie Deezen

Louis de Funès
Ellen DeGeneres
Dom DeLuise
Kat Dennings
Robert De Niro
Portia De Rossi
Zooey Deschanel
Johnny Depp
Adam Devine
Danny DeVito
Cameron Diaz
Peter Dinklage
Downtown
Brian Doyle-Murray**
Fran Drescher
Lena Dunham
Shirley Eaton
Zac Efron
Billy Eichner
Abby Elliott**
Chris Evans (until The New '10s)
Jimmy Fallon**
Anna Faris
Chris Farley**
Marty Feldman
Fernandel
Will Ferrell**
Tina Fey**
W.C. Fields
Nathan Fillion
The Fine Brothers
Colin Firth
Isla Fisher
Jerome Flynn
June Foray
Will Forte**
Michael J. Fox
Jamie Foxx
James Franco
Brendan Fraser
Stan Freberg
Nick Frost
Stephen Fry
Louis de Funès
Josh Gad
Jorge Garcia
Janeane Garofalo**
Brad Garrett
Mark Gatiss
Ricky Gervais
Karen Gillan
Terry Gilliam
Donald Glover
Whoopi Goldberg
John Goodman
Gilbert Gottfried
Hugh Grant
Seth Green
Judy Greer
Clark Gregg
Kathy Griffin
Scott Grimes
Buddy Hackett
Bill Hader**
Tiffany Haddish
Tom Hanks (in the 1980s and early 1990s; not so much now). Trope Namer for Tom Hanks Syndrome.
Alyson Hannigan
Dan Harmon
Neil Patrick Harris
Kevin Hart
Miranda Hart
Phil Hartman**
Charles Hawtrey
Grace Helbig
Ed Helms
Lenny Henry
Jim Henson
Bob Hope
Frankie Howerd
Glenn Howerton
Benny Hill
Jonah Hill
Sarah Hyland
Jessica Hynes
Eric Idle
Eddie Izzard
Marc Evan Jackson
Gillian Jacobs
Hattie Jacques
Kevin James
Sidney James, best known for the Carry On films.
Allison Janney
Richard Jeni
Dwayne Johnson during most of the 2000s.
Jake Johnson
Lia Marie Johnson
Jay Johnston
Brad Jones
Leslie Jones**
Rashida Jones
Terry Jones
Paterson Joseph
Madeline Kahn
Mindy Kaling
Carol Kane
Andy Kaufman
Danny Kaye
Buster Keaton
Michael Keaton
Ellie Kemper
Keegan-Michael Key
Taran Killam**
Greg Kinnear
Kevin Kline
Wayne Knight
Don Knotts
David Koechner
Harvey Korman
Ernie Kovacs
John Krasinski
Lisa Kudrow
Mila Kunis
Ashton Kutcher
Ryan Kwanten
Maurice LaMarche
Phil La Marr
Nathan Lane
Lauren Lapkus
Laurel and Hardy
Hugh Laurie
Martin Lawrence
Cloris Leachman
Denis Leary
Matt LeBlanc
John Leguizamo
Jerry Lewis
Eugene Levy
Christopher Lloyd
Harold Lloyd
Carole Lombard
Justin Long
Shelley Long
Julia Louis-Dreyfus**
Lewis Lovhaug
Joanna Lumley
Jane Lynch
Paul Lynde
Natasha Lyonne
Bernie Mac
Norm MacDonald**
Seth MacFarlane
Patty Maloney
Leslie Mann
Jenna Marbles
James Marsden
Steve Martin
The Marx Brothers
Heather Matarazzo
Rik Mayall
Jayma Mays
Danny McBride
Jenny McCarthy
Melissa McCarthy
Sylvester McCoy
Rob McElhenney
Joel McHale
Tim McInnerny
Michael McKean**
Kate McKinnon**
Stephen Merchant
Seth Meyers**
Lea Michele
Kate Micucci
Dennis Miller**
T.J. Miller
Spike Milligan
David Mitchell
Dudley Moore
Bob Monkhouse
Dylan Moran
Rick Moranis
Heather Morris
Frankie Muniz
Eddie Murphy**
Bill Murray**
Mike Myers**
Bob Newhart
Leslie Nielsen. Trope Namer for Leslie Nielsen Syndrome.
Bill Nighy
Mabel Normand
Tig Notaro
Bob Odenkirk
Nick Offerman
Masi Oka is known for being scene-stealing Plucky Comic Relief.
John Oliver
Mike O'Malley
Ed O'Neill
Kaitlin Olson
Patton Oswalt
Frank Oz
Michael Palin
Randall Park
Jim Parsons
Nasim Pedrad**
Jordan Peele
Simon Pegg
Penn & Teller
Chelsea Peretti
Jon Pertwee
Leslie Phillips
Aubrey Plaza
Amy Poehler**
Brian Posehn
Chris Pratt
Laura Prepon
Richard Pryor
Josh Radnor
Mary Lynn Rajskub (a Stand Up comedian best known for playing Chloe in 24).
Harold Ramis
John C. Reilly
Paul Reubens
Ryan Reynolds
Rhett & Link
Emily Bett Rickards
Don Rickles
John Ritter
Krysten Ritter
Naya Rivera
Craig Robinson
Chris Rock**
Gina Rodriguez
Seth Rogen
James Rolfe
Brandon Routh
Paul Rudd
Maya Rudolph**
Mark Ruffalo
Willie Rushton
Meg Ryan
Bob Saget
Soupy Sales
Andy Samberg**
Adam Sandler**
Susan Sarandon
Jennifer Saunders
Kristen Schaal
Rob Schneider**
Amy Schumer
Terry Scott
Harry Secombe
Amy Sedaris
Jason Segel
Jerry Seinfeld
Peter Sellers
Larry Semon
Alia Shawkat
Wallace Shawn
Harry Shearer
Sarah Silverman**
Phil Silvers
Joan Sims
Jenny Slate**
Tony Slattery
Amy Smart
Michael Smiley
Kevin Smith

Will Smith started this way (The Fresh Prince of Bel-Air), but has gone increasingly serious recently.
Cobie Smulders
Brittany Snow
David Spade**
Timothy Spall
Jordana Spiro
Dino Stamatopoulos
Jon Stewart
Ben Stiller
Emma Stone
Jason Sudeikis**
Eric Sykes
Jeffrey Tambor
Catherine Tate
Jacques Tati
Alan Thicke
Terry-Thomas
The Three Stooges
Analeigh Tipton
Stephen Tobolowsky
Lauren Tom
Marisa Tomei
Lily Tomlin
Patrick Troughton
Dick Van Dyke
Van Kooten En De Bie
Janet Varney
Vince Vaughn
Milana Vayntrub
Christopher Walken
Jessica Walter
Patrick Warburton
Robert Webb
Adam West
Billy West
Mae West
Gemma Whelan
Betty White
Kristen Wiig**
Gene Wilder
Mary Kate Wiles
Allison Williams
Kenneth Williams
Robin Williams
Larry Wilmore
Owen Wilson
Rebel Wilson
Thomas F. Wilson
Barbara Windsor
Henry Winkler
Ariel Winter
Jonathan Winters
Steve Zahn
Renée Zellweger